An analysis is presented to investigate the effect of thermophoresis particle deposition and variable viscosity on Darcy mixed convective heat and mass transfer of a viscous incompressible fluid past a porous wedge in the presence of a chemical reaction. The wall of the wedge is embedded in a uniform Darcian porous medium in order to allow for possible fluid wall suction or injection. The viscosity of the fluid is assumed to be a inverse linear function of temperature. The results are analyzed for the effect of different physical parameters, such as variable viscosity, magnetic, chemical reaction and thermophoresis parameters, on the flow, the heat and mass transfer characteristics.