Let $H_1,H_2,H_3$ be real Hilbert spaces, let $A\colon H_1\to H_3$, $B\colon H_2\to H_3$ be two bounded linear operators. The general multiple-set split common fixed-point problem under consideration in this paper is to \begin{equation} ext{find }xı\cap^p_{i=1}F(U_i), yı\cap^r_{j=1}F(T_j)ext{ such that } Ax=By, \end{equation} where $p,r\geq1$ are integers, $U_i\colon H_1\to H_1$ $(1\leq i\leq p)$ and $T_j\colon H_2\to H_2$ $(1\leq j\leq r)$ are quasi-nonexpansive mappings with nonempty common fixed-point sets $\cap^p_{i=1}F(U_i)=\cap^p_{i=1}\{x\in H_1:U_ix=x\}$ and $\cap^r_{j=1}F(T_j)=\cap^r_{j=1}\{x\in H_2:T_jx=x\}$. Note that, the above problem (1) allows asymmetric and partial relations between the variables $x$ and $y$. If $H_2=H_3$ and $B=I$, then the general multiple-set split common fixed-point problem (1) reduces to the multiple-set split common fixed-point problem proposed by Censor and Segal [J. Convex Anal. 16(2009), 587-600]. In this paper, we introduce simultaneous parallel and cyclic algorithms for the general split common fixed-point problems (1). We introduce a way of selecting the stepsizes such that the implementation of our algorithms does not need any prior information about the operator norms. We prove the weak convergence of the proposed algorithms and apply the proposed algorithms to the multiple-set split feasibility problems. Our results improve and extend the corresponding results announced by many others.