This paper is concerned with integral type boundary value problems of second order singular differential systems with quasi-Laplacian operators on whole lines. A Banach space and a nonlinear completely continuous operator are defined. By using the Banach space and the nonlinear operator, together with the Schauder's fixed point theorem, sufficient conditions to guarantee the existence of at least one unbounded positive solution are established. Finally, we present a concrete example to illustrate the efficiency of the main theorem.