In this paper, we introduce the notions of pre-uniform spaces and pre-proximities and investigate some basic properties about them, where the definition of pre-uniformity here is different from the pre-uniformities which are studied in [1], [8] and [12], respectively. First, we prove that each pre-uniform pre-topology is regular, and give an example to show that there exists a pre-uniform structure on a finite set such that the pre-uniform pre-topology is not discrete. Moreover, we give three methods of generating (strongly) pre-uniformities, that is, the definition of a pre-base, a family of strongly pre-uniform covers, or a family of strongly pre-uniform pseudometrics. As an application, we show that each strongly pre-topological group is completely regular. Finally, we pose the concept of the pre-proximity on a set and discuss some properties of the pre-proximity.