In order to study the influencing factors of cultural and creative industries (CCIs), the Grey Factor Analysis and 30 different indexes are used to empirically analyze the correlation between the influencing factors and the added value of CCIs in Shanghai. At the same time, main environmental factors affecting the development of CCIs are explored. The result shows that technology research and development, policy and government financial support, human resources, social culture, cultural consumption environment, cultural industry basis and development status are important impacting factors on the development of CCIs in Shanghai. Based on the above research results, this paper puts forward some countermeasures and suggestions on the construction of a comprehensive environment to promote the sustainable and healthy development of CCIs.