This paper presents an analysis of organizational changes perceived by the employees in the organizations where Technology Enhanced Learning was facilitated by tools such as wiki, (we)blog, Internet forum and social network, practice often considered as E- learning 2.0. Our research focuses on the technologically advanced organizations, leaders in the ICT and IS adoption. We specifically observe the perception of influence on the organizational structure, organizational culture and the knowledge management processes in the organization. Our findings are that the TEL tools are perceived to have a noteworthy impact on the organizational change in the three mentioned areas, and that the perception of change significantly differs depending on whether the employees are regular or are not regular users for organizational structure and knowledge management processes.