Summarizing basic facts from abstract topological modules over Co\-lom\-be\-au generalized complex numbers we discuss duality of Colombeau algebras. In particular, we focus on generalized delta functionals and operator kernels as elements of dual spaces. A large class of examples is provided by pseudodifferential operators acting on Colombeau algebras. By a refinement of symbol calculus we review a new characterization of the wave front set for generalized functions with applications to microlocal analysis.