Howard and Marić have recently developed nice nonoscillation theorems for the differential equation $$y^{\prime\prime}+ q(t)y= 0 \eqno{\rm (\ast)}$$ by means of regularly varying functions in the sense of Karamata. The purpose of this paper is to show that their results can be fully generalized to differential equations of the form $$(p(t)y^{\prime})^{\prime}+ q(t)y= 0 \eqno{\rm (\ast\ast)}$$ by using the notion of generalized Karamata functions, which is needed to comprehend how delicately the asymptotic behavior of solutions of ($\ast\ast$) is affected by the function $p(t)$.